Each mL of cartridge contains: Insulin Glargine (rDNA) 100 IU, m-Cresol (as preservative) 0.27% w/v and Water for Injection q.s.
Insulin Glargine Injection (rDNA) origin is a recombinant human insulin analogue produced by Recombinant DNA technology. Insulin Glargine differs from human insulin in that the amino acid asparagine at position A2t is replaced by glycine and two arginines are added to the C-terminus of the B chain.
Chemically it is a 21^-Gly-30a-L-Arg-30b-Arg human insulin and has the empirical formula of C267H404N72O78S6 and a molecular weight of 6063.
Insulin Glargine is an insulin analogue, equipotent to human insulin, with a peakless glucose lowering profile and a prolonged duration of action that permits once daily dosing.
Excipients/ Inactive Ingredients: Active: Insulin Glargine (rDNA).
Inactive: m-Cresol (as preservative), Water for Injection.